منابع مشابه
MDR TB Transmission, Singapore
To the Editor: Over the past decade, the proportion of pulmonary multidrug-resistant tuberculosis (MDR TB) cases among Singapore-born patients remained low, whereas that among foreign-born patients was 10 times higher (1,2). Since 2005, Singapore has experienced a sharp increase in the number of MDR TB cases from high-prevalence countries (3). We report local transmission of MDR TB in 2011, fro...
متن کاملMDR-TB and XDR-TB: drug resistance and treatment outcomes.
The subject is quite topical, as TB programmes and clinicians are searching for solutions to treat MDR/XDR-TB most effectively. Recently published studies and a systematic review have shown that XDR-TB is associated with higher probability of failure and death, and lower probability of treatment success than MDR-TB [2–7]. The XDR-TB-defining drugs have been studied to evaluate their role in det...
متن کاملMDR / XDR - TB : where do we stand ?
Tuberculosis (TB) is one of the leading causes of death due to an infectious disease, second only to HIV/AIDS worldwide. It is estimated that approximately one third of the world’s population is infected with Mycobacterium tuberculosis, and 10% of infected individuals will develop active TB at some point in their lives. MDR-TB or multidrugresistant tuberculosis is a specific form of drug resist...
متن کاملEpidemiology of Multidrug Resistant Tuberculosis (MDR-TB)
The history of tuberculosis treatment has observed sequential development of resistance to anti-tuberculosis drugs over the decades. Para amino salicylic acid (PAS) and isoniazid (INH) were introduced to reduce the development of streptomycin (SM) resistance, which heralded the era of combination treatment for tuberculosis [1]. Within 20 years, resistance to both INH and SM was already a challe...
متن کاملPreventing nosocomial MDR TB transmission in sub Saharan Africa: where are we at?
BACKGROUND In sub Saharan Africa, the cocktail of many advanced HIV-infected susceptible hosts, poor TB treatment success rates, a lack of airborne infection control, limited drug-resistance testing (DST) have resulted in HIV-infected individuals being disproportionately represented in Multi drug resistant Tuberculosis (MDR-TB) cases. The prevailing application of the WHO re-treatment protocol...
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ژورنال
عنوان ژورنال: Emerging Infectious Diseases
سال: 2013
ISSN: 1080-6040,1080-6059
DOI: 10.3201/eid1907.120372